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In women, anabolic steroids can cause: facial hair growth and body hair loss of breasts swelling of the clitoris a deepened voice an increased sex drive problems with periods hair loss severe acneacne with red discoloration of the skin problems with acne, such as breakouts, pimple outbreaks and abscesses a rapid growth of the breasts increased hair growth and hair loss in the area of the face, such as in the chin, chest, armpits and groin and elsewhere in the body In men, anabolic steroids can cause: the testicles hair loss and hair thinning hair thinning of the scalp and underarms increased growth of beard a loss in penis color changes the testicles How long do steroids stay in the body? Steroids are absorbed rapidly into the body. Some of the absorption occurs immediately after use, some more quickly. Steroid use can be harmful if used while pregnant or if taken at the same time as chemotherapy (blood cancer treatment). The absorption can also be delayed; however, it is usually faster once the dose is absorbed. The effects of high doses of steroids may result from multiple, high doses. The metabolism of steroids in humans are complex. The most common metabolic pathways for steroids are the cytoplasmic, endoplasmic, and mitochondrial pathways. In the cytoplasmic pathway, steroids are converted into dehydroepiandrosterone (DHEA) in cells. DHEA then moves into the bloodstream and reaches the kidneys where it is converted into cortisol. This leads to an increase in the body's production of cortisol (stress hormone) and other stress hormones. When corticosteroids cross the blood-brain-barrier, they are released into the brain to have their effects. Cortisol can bind to adrenal receptors, blocking the release of other stress hormones. However, this does not stop the effects of the steroids directly. The adrenal and vasopressin systems are in constant balance. Both systems have a positive and negative feedback loop. If one system becomes overloaded, the other system can reduce its production of stress hormones and/or can produce cortisol to control and maintain normal levels. Steroids are also released into the bloodstream when they interact with enzymes (bile acids), hormones, and other compounds. These chemicals can cause a number of changes and/or disorders in the body. In addition, steroids can interact with other drugs or medications. Steroids do interact with certain medications and medications can affect testosterone production. Some physicians prescribe testosterone creams to suppress the effects of corticosteroids and to treat hypogonadotropic hypogonadism (low testosterone). Related Article:
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